Connectivity Map. Premium Photo US Digital Connectivity Map Cyber Tech and Data Flow The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease This web interface is designed to allow biologists.
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But this remains a daunting task, and even the most inspired researchers still have to resort to laborious screens of genetic or chemical libraries. Here, we report more than a 1,000-fold scale-up of the CMap as part of the NIH LINCS Consortium, made possible by a new, low-cost, high-throughput reduced representation.
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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease We demonstrate that this "Connectivity Map" resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs The data is used to find the functional connections between drugs, genes, and diseases through the transitory feature of common gene-expression changes.
This World Map Shows Every Device Connected To The Business. We demonstrate that this "Connectivity Map" resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs The Broad Institute's Connectivity Map is a collection of genome-wide, transcriptional expression data from cultured human cells
web mapping Examples of geovisualizations of global connectivity. The Connectivity Map is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of decisive functional connections between drugs, genes, and diseases The Research Article "The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease" (29 Sept